反应 #87648

反应方程式

5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoic acid

oxalyl chloride

ammonia

→

desired product

5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-methoxybenzamide

溶剂

THF

反应条件

后处理

1. 1
   其他The title compound was prepared

实验过程

The title compound was prepared according to the procedure described in step-2 of Intermediate-26 by using 5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoic acid (1.0 g), oxalyl chloride (1.0 mL), THF (50 mL) and ammonia gas to afford 0.800 g of the desired product.

来源