反应 #852

反应方程式

p-Phenylenediamine

benzylisothiocyanate

→

colorless crystal

收率 61.6%

1,4-di(benzylthiocarbamoylamino)benzene

收率 61.6%

溶剂

ethyl acetate

反应条件

后处理

1. 1
   温度After cooling
2. 2
   过滤the reaction mixture was filtered
3. 3
   洗涤washed with ethylacetate/n-hexane

实验过程

p-Phenylenediamine (2.707 g, 25 mM) was dissolved in 20 ml of ethyl acetate, and 2 equivalents of benzylisothiocyanate (7.461 g, 50 mM) were added. The mixture was stirred at 80° C. for 30 minutes. After cooling, the reaction mixture was filtered, and washed with ethylacetate/n-hexane to obtain 6.26 g (61.6% yield) of a colorless crystal of compound A-25.

来源