反应 #82335

反应方程式

N2 (benzyloxycarbonyl)-N1 -isopentyl-L-prolinamide

→

N1 -isopentyl-L-prolinamide

收率 111.5%

溶剂

ethanol

反应条件

后处理

1. 1
   其他The catalyst was removed by filtration
2. 2
   其他the filtrate was evaporated

实验过程

A solution of 5.73 g of N2 -(benzyloxycarbonyl)-N1 -isopentyl-L-prolinamide in 600 ml of ethanol was hydrogenated over 0.8 g of 10% palladium-on-carbon catalyst for 3.75 hours. The catalyst was removed by filtration and the filtrate was evaporated to give 3.4 g of N1 -isopentyl-L-prolinamide as an oil which was used without further purification.

来源