反应 #81759

反应方程式

2-methanesulfonyloxynonane

triiodophenol

potassium carbonate

2-(2,4,6-triiodophenoxy)pentadecane

2-(2,4,6-triiodophenoxy)pentadecane

→

2-(2,4,6-triiodophenoxy)nonane

收率 68.0%

溶剂

DMF

—

hexanes

反应条件

后处理

1. 1
   其他to provide a light brown oil

实验过程

The 2-methanesulfonyloxynonane (22.8 g, 102 mmol), triiodophenol (48.8 g, 103 mmol) and potassium carbonate (14.2 g, 103 mmol) were reacted in DMF (206 ml) as per 2-(2,4,6-triiodophenoxy)pentadecane except at an oil bath temperature of 82° C. for 14 hrs. The reaction was processed as for 2-(2,4,6-triiodophenoxy)pentadecane to provide a light brown oil. Flash column chromatography (silica, hexanes) provided 2-(2,4,6-triiodophenoxy)nonane (40.8 g, 68.0%).

来源