反应 #80686

反应方程式

Methyl isocyanate

2,4-difluoroaniline

→

title product

2,4-Difluorophenyl-3-methylurea

溶剂

toluene

反应条件

后处理

1. 1
   过滤filtered
2. 2
   其他to obtain a solid
3. 3
   洗涤The solid is washed with hexanes
4. 4
   其他air-dried

实验过程

Methyl isocyanate (9.6 g, 10 mL, 0.174 mol) is added to a solution of 2,4-difluoroaniline (15 g, 0.116 mol) in toluene. The reaction mixture is stirred for 1 hour and filtered to obtain a solid. The solid is washed with hexanes and air-dried to give the title product as an off-white solid, mp 182°-183° C.

来源