反应 #80475

反应方程式

compound ( 2 )

2-dimethylaminomethyl-1, 2-dihydro-1-pyrrolizinone

4-methylaniline

→

yellow solid

收率 83.0%

2-(4-methylphenyamino)methyl-1, 2-dihydro-1-pyrrolizinone

收率 83.0%

反应条件

实验过程

A solution of 17.5 g, compound (2) and 10 g 4-methylaniline was allowed to stand at room temperature for 12 hours. 22 g yellow solid was obtained after filtering. Recrystallized from ethanol, 19 g (5) was obtained as a white crystal, mp 112°-114° C., yield 83%.

来源