反应 #79444

反应方程式

3,4-dichlorobenzoyl chloride

Fmoc-L-histidine

Fmoc-L-leucine

thiophene-2-carboxaldehyde

→

title compound

5-Furan-2-yl-2-(1H-imidazol-4-ylmethyl)-1-(1-o-tolyl-methanoyl)-pyrrolidine-2,4-dicarboxylic acid

反应条件

实验过程

Following the procedure of Example 28(a)-28(d), except beginning with Wang bound Fmoc-L-histidine (Trt) instead of Wang bound Fmoc-L-leucine, and substituting furan-2-carboxaldehyde for thiophene-2-carboxaldehyde, and substituting o-toluoyl chloride for 3,4-dichlorobenzoyl chloride, the title compound was prepared as a solid. MS [M+H]+424.4

来源