反应 #792146

反应方程式

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one

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title compound

收率 59.6%

1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)propan-1-one

收率 59.6%

溶剂

methanol

反应条件

后处理

1. 1
   其他to give a yellow solution
2. 2
   过滤The reaction mixture was filtered
3. 3
   其他evaporated
4. 4
   洗涤the solid residue was washed with diethylether
5. 5
   其他dried

实验过程

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one (0.5 g, 1.857 mmol) was added to methanol (50 ml) to give a yellow solution. Palladium on carbon (0.05 g) was added. Product was hydrogenated while stirring till conversion was completed (checked by TLC). The reaction mixture was filtered, evaporated and the solid residue was washed with diethylether, and dried to yield 0.3 g (57%) of the title compound.

来源