反应 #78196

反应方程式

3-hydroxybenzoic acid

iodine monochloride

→

title compound

3-Hydroxy-4-iodobenzoic acid

溶剂

acetic acid

反应条件

后处理

1. 1
   其他the solvent was evaporated under reduced pressure
2. 2
   洗涤The residue was washed with 500 ml of 1% aqueous sodium thiosulfate solution twice
3. 3
   干燥with 500 ml of water twice and then dried to solid at 80° C. under reduced pressure

实验过程

30.0 g (217 mmol) of 3-hydroxybenzoic acid was dissolved in 200 ml of acetic acid. 53.0 g (326 mmol) of iodine monochloride was added to the obtained solution at room temperature. They were stirred at 45° C. for 15 hours and then the solvent was evaporated under reduced pressure. The residue was washed with 500 ml of 1% aqueous sodium thiosulfate solution twice and with 500 ml of water twice and then dried to solid at 80° C. under reduced pressure to obtain the title compound.

来源