反应 #76898

ord-301af24f085b4ddc870f183af569eb4f

反应方程式

COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC
1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NC1CCc2ccccc21
1-amino-indane
→
COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NC2CCc3ccccc32)cc1OC
2-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide

反应物

COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC
1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NC1CCc2ccccc21
1-amino-indane

试剂

无

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

prepared by reaction of 1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 1-amino-indane

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US06703392B2uspto-grants-2004_03