反应 #76886

ord-60cc0e959c3242719142384e82c308da

反应方程式

COc1cccc(CC2NCCc3cc(OC)c(OC)cc32)c1
1-(3-Methoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
Cc1cccc(CN)c1
3-methyl-benzylamine
→
COc1cccc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2cccc(C)c2)c1
2-[1-(3-Methoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(3-methyl-benzyl)-acetamide

反应物

COc1cccc(CC2NCCc3cc(OC)c(OC)cc32)c1
1-(3-Methoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
Cc1cccc(CN)c1
3-methyl-benzylamine

试剂

无

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

prepared by reaction of 1-(3-Methoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline and 2-bromoacetyl bromide with 3-methyl-benzylamine

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US06703392B2uspto-grants-2004_03