反应 #7625

反应方程式

acetylchloride

2-amino-pyridine

cyclohexylisonitrile

cyclohexane carbaldehyde

→

1-acetyl-2-cyclohexyl-3-cyclohexylamino-imidazo[1,2-a]pyridin-1-ium chloride

溶剂

perchloric acid

反应条件

实验过程

Example 23 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyridine (0.1 M, DCM), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) cyclohexane carbaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.

来源