反应 #75657

反应方程式

3,5-dichloroaniline

ethylglyoxalate

4-tert-butylstyrene

trifluoroacetic acid

→

Compound 25

收率 89.0%

4-(4-tert-butylphenyl)-5,7-dichloro-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid Ethyl Ester

收率 89.0%

溶剂

acetonitrile

反应条件

实验过程

Compound 25 was prepared in a yield of 89% by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 4-tert-butylstyrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

来源