反应 #75640

反应方程式

Compound 1

7,9-dichloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic Acid Ethyl Ester

sodium hydroxide

→

7,9-dichloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic Acid

溶剂

ethanol

反应条件

后处理

1. 1
   浓缩The ethanolic solution was concentrated to small volume on a rotary evaporator
2. 2
   其他reacted with 6N HCl
3. 3
   萃取the aqueous solution extracted three times over ether
4. 4
   洗涤The organic phase was washed neutral with water
5. 5
   干燥dried over magnesium sulphate
6. 6
   浓缩concentrated to a reduced volume on a rotary evaporator

实验过程

Compound 1 was saponified with 1.0 ml sodium hydroxide solution (6N, water) in 20.0 ml ethanol. The ethanolic solution was concentrated to small volume on a rotary evaporator, the residue was taken up in water, reacted with 6N HCl and the aqueous solution extracted three times over ether. The organic phase was washed neutral with water, dried over magnesium sulphate and concentrated to a reduced volume on a rotary evaporator.

来源