反应 #75079

反应方程式

ethylene

cis-1-bromo-1-hexene

morpholine

tri-o-tolylphosphine

→

cis-1,3-octadiene

收率 5.0%

N-oct-3-en-2-ylmorpholine

收率 84.0%

N-oct-2-en-4-ylmorpholine

收率 8.0%

溶剂

acetonitrile

反应条件

后处理

1. 1
   温度After cooling
2. 2
   其他the reaction products were isolated as in Example 1

实验过程

A mixture of 10 mmoles cis-1-bromo-1-hexene, 30 mmoles morpholine, 4 ml of acetonitrile, 0.10 mmole palladium acetate and 0.20 mmole of tri-o-tolylphosphine was heated in a pressure vessel under 200 psig of ethylene at 100° C. for 2 hrs. After cooling, the pressure was released and the reaction products were isolated as in Example 1. There was obtained about 5% cis-1,3-octadiene, 84% N-oct-3-en-2-ylmorpholine and 8% N-oct-2-en-4-ylmorpholine.

来源