反应 #7501

反应方程式

title compound

Methyl (2E)-[(2-chlorophenyl)hydrazono]acetate

N-bromosuccinimide

→

title compound

收率 71.3%

Methyl (2Z)-bromo[(2-chlorophenyl)hydrazono]acetate

收率 71.3%

溶剂

tetrahydrofuran

反应条件

后处理

1. 1
   浓缩The mixture was concentrated
2. 2
   萃取extracted with hexane
3. 3
   浓缩the hexane solution was concentrated

实验过程

To a solution of the title compound of Step A (16.5 g, 77 mmol) in tetrahydrofuran (150 mL) was added N-bromosuccinimide (13.7 g, 77 mmol) and the mixture was stirred at ambient temperature for 2 hours. The mixture was concentrated and extracted with hexane and the hexane solution was concentrated to give the title compound of Step B (16 g) as an orange solid.

来源