反应 #742308
ord-d54b4eb33b0c4bd49354dd0216ad804c
反应方程式
4,4′-(2-aminoethylidene)bis-phenol
4,4′-(2-aminoethylidene)bisphenol
(2R,3S,4R,5R)-2-(2-benzyl-2H-tetrazol-5-yl)-5-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol
Intermediate A
4,4′-(2-aminoethylidene)bisphenol
→
title compound
(2R,3S,4R,5R)-2-(2-Benzyl-2H-tetrazol-5-yl)-5-{6-[2,2-bis-(4-hydroxy-phenyl)ethylamino]-2 chloro-purin-9-yl}tetrahydro-furan-3,4-diol
反应物
试剂
无
反应条件
详细条件
See reaction.notes.procedure_details.
实验过程
The title compound is prepared in an analogous fashion to (2R,3S,4R,5R)-2-(2-benzyl-2H-tetrazol-5-yl)-5-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol (WO 99/38877) by replacing 2,2-diphenylethylamine with 4,4′-(2-aminoethylidene)bis-phenol (Intermediate A).