反应 #742248

反应方程式

(E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid

citronellol

p-toluene-sulfonic acid

water

→

colourless oil

(E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 3,7 dimethyl-oct-6-enyl ester

溶剂

cyclohexane

hexane

反应条件

后处理

1. 1
   温度Then the reaction mixture was cooled down
2. 2
   洗涤washed
3. 3
   其他The organic phase was dried
4. 4
   过滤filtered
5. 5
   其他evaporated to dryness
6. 6
   其他The resulting yellow oil was purified by chromatography

实验过程

A solution of 6 0 g of (E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid, 5.3 g of citronellol and 1 g of p-toluene-sulfonic acid in 150 ml of cyclohexane was refluxed for 6.5 hours using a water separator. Then the reaction mixture was cooled down, diluted with hexane and washed to neutrality with saturated sodium bicarbonate and water. The organic phase was dried, filtered and evaporated to dryness. The resulting yellow oil was purified by chromatography to yield 6.45 g of a colourless oil.

来源