反应 #742244

反应方程式

(carbethoxyethylidene)triphenyl phosphorane

salicylaldehyde

→

(E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid ethyl ester

溶剂

toluene

toluene

反应条件

后处理

1. 1
   温度while cooling in an ice-bath
2. 2
   洗涤washed

实验过程

To a solution of 75.0 g (carbethoxyethylidene)triphenyl phosphorane in 350 ml of toluene, 23.2 g of salicylaldehyde was dropped in at 20° C. while cooling in an ice-bath. After stirring at room temperature for 90 mn., the reaction mixture was diluted with toluene and washed to neutrality with water.

来源