反应 #72533

反应方程式

trichloroacetyl chloride

pyrrole

potassium carbonate

→

title product

2,2,2-Trichloro-1-(1H-pyrrol-2-yl)ethanone

溶剂

ethyl ether

water

ethyl ether

反应条件

后处理

1. 1
   其他The phases are separated
2. 2
   干燥the organic phase is dried over sodium sulphate
3. 3
   过滤filtered
4. 4
   workup.ADDITIONActive carbon is added to this organic phase
5. 5
   workup.STIRRINGAfter stirring for 5 minutes
6. 6
   过滤the organic phase is filtered
7. 7
   其他evaporated to dryness

实验过程

To a solution of trichloroacetyl chloride (160.7 mmoles) in ethyl ether (26 ml) there is added, dropwise over a period of 3 hours, a solution of pyrrole (149 mmoles) in ethyl ether (83 ml). After stirring for a further hour, a solution of potassium carbonate (94 mmoles) in water (39 ml) is added dropwise. The phases are separated and the organic phase is dried over sodium sulphate and filtered. Active carbon is added to this organic phase. After stirring for 5 minutes, the organic phase is filtered and evaporated to dryness to yield the title product.

来源