反应 #696695

反应方程式

1,4-diaminobutane

triethylamine

2-chloro-2-methyl-3-nitrosopentane

→

2-(4-aminobutyl)amino-2-methyl-3-pentanone oxime

溶剂

acetonitrile

acetonitrile

反应条件

后处理

1. 1
   其他to precipitate
2. 2
   workup.STIRRINGThe reaction mixture was stirred overnight
3. 3
   过滤the product was filtered off
4. 4
   其他dried in vacuo
5. 5
   其他to give a white powder, (0.5 g; 86%)

实验过程

To a stirred solution of 1,4-diaminobutane (0.26 g; 2.9 mmol) and triethylamine (0.33 g; 3.2 mmol) in acetonitrile (5 ml) was added a solution of 2-chloro-2-methyl-3-nitrosopentane (0.485 g; 3.24 mmol) in acetonitrile (5 ml). After stirring for ca 10 minutes the product began to precipitate. The reaction mixture was stirred overnight and the product was filtered off and dried in vacuo to give a white powder, (0.5 g; 86%).

来源