反应 #684948

反应方程式

Thionyl chloride

4-n-butylbenzyl alcohol

→

title compound

收率 104.9%

1-(Chloromethyl)-4-n-butylbenzene

收率 104.9%

溶剂

ether

反应条件

后处理

1. 1
   其他After concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene

实验过程

Thionyl chloride (2.5 ml, 34 mmol) was added to a solution of 4-n-butylbenzyl alcohol (2.0 g, 12 mmol) in ether (25 ml), and this mixture was stirred at room temperature for 3 hours. After concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene to give the title compound (2.3 g). This compound was used in the following reaction without purification.

来源