反应 #684939

反应方程式

4-methoxy-4′-(di-p-tolylamino)stilbene

sodium ethanethiolate

water

hydrochloric acid

→

4-hydroxy-4′-(di-p-tolylamino)stilbene

溶剂

N,N-dimethylformamide

反应条件

后处理

1. 1
   其他reacted for 5 hours at 130° C
2. 2
   温度The mixture is cooled down
3. 3
   萃取The objective material is extracted
4. 4
   洗涤The extracted liquid is washed with water
5. 5
   其他dried
6. 6
   其他The crude objective material is prepared
7. 7
   其他by removing the solvent (i.e., N,N-dimethylformamide)
8. 8
   其他Further, the crude objective material is purified with a column chromatography

实验过程

The above-prepared 4-methoxy-4′-(di-p-tolylamino)stilbene and twice equimolar amount of sodium ethanethiolate are dissolved in N,N-dimethylformamide, and reacted for 5 hours at 130° C. The mixture is cooled down, and then poured into water and neutralized with hydrochloric acid. The objective material is extracted therefrom using acetic acid. The extracted liquid is washed with water, and then dried. The crude objective material is prepared by removing the solvent (i.e., N,N-dimethylformamide) therefrom. Further, the crude objective material is purified with a column chromatography using silica gel. Thus, 4-hydroxy-4′-(di-p-tolylamino)stilbene (i.e., objective material) is prepared.

来源