反应 #674366

反应方程式

A1

3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

indoline

→

3-[(4-(Indolin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethane sulfonamide

反应条件

后处理

1. 1
   其他B52 was prepared

实验过程

B52 was prepared following the general procedure reported for B10 using A1 and indoline; yield: 76.2 mg (20%), pale yellow solid. 1H NMR (400 MHz, d6-DMSO, 300K) δ 3.11-3.18 (m, 2H), 4.14-4.26 (m, 2H), 4.23 (s, 2H), 6.84 (s, 2H), 6.97 (t, J=7.1 Hz, 1H), 7.01-7.09 (bm, 1H), 7.13-7.21 (bm, 1H), 7.25 (d, J=7.0 Hz, 1H), 7.33 (t, J=7.7 Hz, 1H), 7.64-7.90 (bm, 2H), 8.29-8.41 (bm, 1H), 8.43 (s, 1H), 9.90 (s, 1H). MS (ES) C18H18N6O2S requires: 382. found: 383 (M+H)+.

来源