反应 #674363

反应方程式

A1

3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

2,3-dihydro-1H-pyrrolo[3,4-c]pyridine hydrochloride

→

3-[(4-(1H-Pyrrolo[3,4-c]pyridin-2(3H)-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide

反应条件

后处理

1. 1
   其他B49 was prepared

实验过程

B49 was prepared following the general procedure reported for B10 using A1 and 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine hydrochloride; yield: 139.0 mg (36%), brown amorphous solid. 1H NMR (400 MHz, d6-DMSO, 300K) δ 4.27 (s, 2H), 4.92 (s, 2H), 4.97 and 4.99 (2 s, 2H), 6.87 and 6.88 (2 s, 2H), 7.01 (d, J=7.5 Hz, 1H), 7.30 (t, J=7.9 Hz, 1H), 7.59-7.72 (m, 2H), 7.98 (bs, 1H), 8.31 (d, J=1.4 Hz, 1H), 8.62 (t, J=6.0 Hz, 1H), 8.76 (d, J=5.7 Hz, 1H), 9.82 (s, 1H). MS (ES) C17H17N7O2S requires: 383. found: 384 (M+H)+.

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