反应 #674331

反应方程式

A1

3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

pyrrolidine

→

3-[(4-(Pyrrolidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethane sulfonamide

反应条件

后处理

1. 1
   其他B14 was prepared

实验过程

B14 was prepared following the general procedure reported for B10 using A1 and pyrrolidine. Yield: 96.6 mg (29%), colorless amorphous solid. 1H NMR (400 MHz, d6-DMSO, 300K) δ 1.84-1.96 (m, 4H), 3.43-3.55 (m, 4H), 4.18 (s, 2H), 6.81 (s, 2H), 6.96 (d, J=7.6 Hz, 1H), 7.25 (t, J=7.9 Hz, 1H), 7.69 (d, J=9.5 Hz, 1H), 7.86 (s, 1H), 8.18 (s, 1H), 9.59 (s, 1H). MS (ES) C14H18N6O2S requires: 334. found: 335 (M+H)+.

来源