反应 #6681

反应方程式

Cs2CO3

benzyl bromide

BzBn

ethyl 4-hydroxybenzoate

→

Ethyl 4-benzyloxybenzoate

收率 100.0%

溶剂

DMF

water

反应条件

后处理

1. 1
   其他the product was collected by extraction
2. 2
   洗涤The organic solution was washed with brine
3. 3
   干燥dried over MgSO4
4. 4
   其他After evaporation of solvent
5. 5
   其他pure product was obtained in yield of 100%

实验过程

35 mmol of benzyl bromide (BzBn, 35 mmol of ethyl 4-hydroxybenzoate (10), 14 g of Cs2CO3 and 40 ml of DMF were combined and stirred at RT ove night. Then the reaction mixture was poured into water and the product was collected by extraction. The organic solution was washed with brine and dried over MgSO4. After evaporation of solvent, pure product was obtained in yield of 100%.

来源