反应 #657263

反应方程式

methylphenidate HCl

→

Methylphenidate

溶剂

water

反应条件

后处理

1. 1
   其他The wet pellets are dried (Fluid Air Model#0050)
2. 2
   过滤sieved (30 mesh<Acceptable<20 mesh)

实验过程

In a preferred manufacturing process, methylphenidate HCl and microcrystalline cellulose (Avicel PH-101) are blended in a Hobart Mixer. Purified water is added to the dry mixture and the wet granulation is extruded (MG-55 Multi granulator). The extrudate is then spheronized into pellets (Caleva Model# SPH250). The wet pellets are dried (Fluid Air Model#0050) and sieved (30 mesh<Acceptable<20 mesh).

来源