反应 #65645

反应方程式

cyclohexylamine

atropic acid

N-methylmorpholine

iso-butyl chloroformate

→

product

收率 28.9%

N-Cyclohexyl-2-phenylpropenamide

收率 28.9%

反应条件

后处理

1. 1
   其他The crude product was purified by recrystallisation from cyclohexane

实验过程

This compound was made from atropic acid (10.48 g, 70.8 mmol), N-methylmorpholine (7.8 ml, 70.9 mmol), iso-butyl chloroformate (9.2 ml, 70.9 mmol), and cyclohexylamine (8.1 ml, 70.7 mmol) using the procedure described in Example 3. The crude product was purified by recrystallisation from cyclohexane to give the product (4.69 g), as white crystals, m.p. 131°-133°. (Found: C, 78.7; H, 8.8; N, 5.95. C15H19NO requires C, 78.6; H, 8.35; N, 6.1%.)

来源