反应 #652991

反应方程式

NaNO2

SnCl2.2H2O

4-amino-5,6,7,8-tetrahydro-1-naphthalenecarboxylic acid

→

hydrazine

收率 73.3%

4-Hydrazino-5,6,7,8-tetrahydro-1-naphthalenecarboxylic acid hydrochloride

收率 73.3%

溶剂

water

HCl

HCl

反应条件

后处理

1. 1
   workup.STIRRINGThe mixture is stirred for 1 hour at RT
2. 2
   过滤filtered
3. 3
   洗涤the product is washed with concentrated HCl
4. 4
   其他dried under a stream of dry nitrogen

实验过程

A solution of 0.26 g of NaNO2 in 1 ml of water is added to a solution, cooled to −5° C., of 0.73 g of 4-amino-5,6,7,8-tetrahydro-1-naphthalenecarboxylic acid in 10 ml of concentrated HCl. After one and a half hours of stirring at −5° C., a solution of 3.4 g of SnCl2.2H2O in 34 ml of concentrated HCl is added at −5° C. The mixture is stirred for 1 hour at RT and filtered, and the product is washed with concentrated HCl and dried under a stream of dry nitrogen to obtain 0.67 g of the expected hydrazine.

来源