反应 #65060

反应方程式

Sodium cyanide

4-chlorobenzenediazonium tetrafluoroborate

→

4-Chlorobenzonitrile

收率 75.0%

溶剂

water

water

反应条件

后处理

1. 1
   workup.STIRRINGstirred until it
2. 2
   其他to react at room temperature
3. 3
   萃取The mixture was extracted by ethyl acetate
4. 4
   其他had been formed in 75% yield

实验过程

Sodium cyanide (2.94 g; 0.06 mol) was added to water and stirred. Cuprous cyanide (2.7 g; 0.03 mol) was added to the mixture stirred until it became homogeneous. 4-chlorobenzenediazonium tetrafluoroborate (5.66 g; 0.025 mol) in water (10 ml) was added to one portion. The mixture was allowed to react at room temperature. The mixture was extracted by ethyl acetate and the extract analysed by means of gas chromatography which indicated that 4-chlorobenzonitrile had been formed in 75% yield.

来源