反应 #64972

反应方程式

7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

NaOH

K2CO3

→

1,2-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

溶剂

water

反应条件

后处理

1. 1
   萃取extracted several times with CHCl3
2. 2
   干燥the extract is dried over K2CO3
3. 3
   浓缩concentrated
4. 4
   workup.DISTILLATIONthe residue is distilled

实验过程

11.8 g (64mmol) of 7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane are heated under reflux with 12 g of NaOH in 36 ml of water overnight. The mixture is saturated with K2CO3 and extracted several times with CHCl3, the extract is dried over K2CO3 and concentrated and the residue is distilled.

来源