反应 #64755

反应方程式

propylene glycol methyl ether

cyclohexene oxide

PM

→

2-hydroxycyclohexyloxymethoxypropane

收率 27.4%

反应条件

后处理

1. 1
   其他equipped with a reflux tube
2. 2
   温度under reflux at a temperature for a reflux reaction for 10 hours
3. 3
   其他Results of the analysis of the resultant
4. 4
   其他reaction mixture by GC
5. 5
   其他Then, the obtained reaction mixture
6. 6
   workup.DISTILLATIONwas subjected to distillation

实验过程

45 g (0.5 mole) of propylene glycol methyl ether (PM), 33 g (0.33 mole) of cyclohexene oxide and 0.3 g (0.007 mole) of sodium hydroxide were charged in a 100 ml eggplant type flask equipped with a reflux tube, and a reaction was allowed to proceed under reflux at a temperature for a reflux reaction for 10 hours. Results of the analysis of the resultant reaction mixture by GC showed that the conversion of PM was 20%. Then, the obtained reaction mixture was subjected to distillation, to thereby obtain 17 g of 2-hydroxycyclohexyloxymethoxypropane, i.e., propylene glycol methyl 2-hydroxycyclohexyl ether (hereinafter referred to as "PGMHCHE"). The IR spectrum of the product is shown in FIG. 3. Other properties of the product were measured and results are shown in Table 1.

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