反应 #6428

反应方程式

2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxyphenol

butyl bromide

potassium carbonate

→

1-butyloxy-2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxybenzene

溶剂

dimethylformamide

反应条件

后处理

1. 1
   温度After cooling
2. 2
   过滤the inorganic salts are filtered off with suction
3. 3
   浓缩the filtrate is concentrated
4. 4
   workup.ADDITIONwater is added

实验过程

0.1 mol of 2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxyphenol, 0.11 mol of butyl bromide and 0.11 mol of potassium carbonate are heated for 16 hours at 100° in 100 ml of dimethylformamide (DMF). After cooling, the inorganic salts are filtered off with suction, the filtrate is concentrated, and water is added. 1-butyloxy-2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxybenzene is obtained by extraction with dichloromethane.

来源