反应 #64248

ord-086d97b933f84449a5902622d6ad17f2

反应方程式

CC(=O)SCC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
2-acetylmercapto-N-(trans-4-nitroxycyclohexyl)acetic acid amide
N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
trans-4-nitroxycyclohexylamine
CC(=O)SCC(=O)Cl
2-acetylmercaptoacetic acid chloride
→
CCC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
trans-N-propionyl-4-nitroxycyclohexylamine
收率 67.0%

反应物

CC(=O)SCC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
2-acetylmercapto-N-(trans-4-nitroxycyclohexyl)acetic acid amide
N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
trans-4-nitroxycyclohexylamine
CC(=O)SCC(=O)Cl
2-acetylmercaptoacetic acid chloride

试剂

无

反应条件

详细条件
See reaction.notes.procedure_details.

实验过程

2-acetylmercapto-N-(trans-4-nitroxycyclohexyl)acetic acid amide from trans-4-nitroxycyclohexylamine and 2-acetylmercaptoacetic acid chloride melting point: 127°-129° C. (ether), yield: 67% of theory.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US05411989uspto-grants-1995_05