反应 #640589

反应方程式

cyanogen bromide

(±)-trans-1,2-cyclohexanediamine

3,4-difluorobenzaldehyde

→

title compound

(±)-trans-1,3-Bis-(3,4-difluoro-benzyl)octahydro-benzoimidazol-2-ylideneamine

反应条件

后处理

1. 1
   其他the reaction mixture was evaporated to dryness
2. 2
   洗涤the crude product washed with ether
3. 3
   其他recrystallized from MeOH

实验过程

The title compound was prepared from (±)-trans-1,2-cyclohexanediamine and 3,4-difluorobenzaldehyde by Procedure C. After reacting with cyanogen bromide, the reaction mixture was evaporated to dryness and the crude product washed with ether and recrystallized from MeOH to give the title compound as the hydrogen bromide salt (mp 238-240° C.). MS (ES+) m/z 392 ([M+1]+, 100).

来源