反应 #637124

反应方程式

tert-Butyl 4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate

triphenyl(3-phenylbutyl)phosphonium iodide

→

tert-Butyl 4-{4-[(1Z)-4-phenylpent-1-en-1-yl]-1,3-thiazol-2-yl}piperidine-1-carboxylate

反应条件

后处理

1. 1
   其他purified

实验过程

tert-Butyl 4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate (1.00 g) is reacted with triphenyl(3-phenylbutyl)phosphonium iodide (3.53 g) and purified as described in IV-3. This gives tert-butyl 4-{4-[(1Z)-4-phenylpent-1-en-1-yl]-1,3-thiazol-2-yl}piperidine-1-carboxylate (1.23 g) in form of the Z isomer.

来源