反应 #63711

反应方程式

acetone

phenol

chlorotrimethyl silane

butanethiol

chlorobenzene

→

bisphenol A

收率 83.0%

反应条件

后处理

1. 1
   workup.ADDITIONInto a 250-millimiter 3-necked round-bottomed flask was charged
2. 2
   其他On completion of the reaction
3. 3
   温度the reaction mixture was cooled to room temperature
4. 4
   过滤filtered
5. 5
   其他The solid product resulting
6. 6
   过滤filtered
7. 7
   洗涤washed twice with chlorobenzene
8. 8
   其他Purification
9. 9
   其他by recrystallization from methanol and water

实验过程

Into a 250-millimiter 3-necked round-bottomed flask was charged a mixture of 11.6 grams (0.20 mole) of acetone, 75 grams (0.80 mole) of phenol, 22 grams (0.20 mole) of chlorotrimethyl silane, and 0.10 gram of butanethiol. The resulting mixture was stirred mechanically and heated at 55° C. under a nitrogen atmosphere for 3 hours. On completion of the reaction, the reaction mixture was cooled to room temperature and filtered. The solid product resulting was slurried up in chlorobenzene, filtered and washed twice with chlorobenzene. Purification by recrystallization from methanol and water afforded bisphenol A with a purity of 99.5 percent in a 83 percent yield.

来源