反应 #632015

ord-9c40983943a74fc7b373430c458d5e26

反应方程式

CC(C)(C)NC(=O)O.COCC1(S(N)(=O)=O)CC1
1-methoxymethylcyclopropylsulfonylamine tert-butylcarbamate
Cc1noc(C)c1N=C=O
3,5-dimethylisoxazole-4-isocyanate
CC(C)(C)NC(=O)O.Cc1noc(C)c1NC(=O)C1(S(N)(=O)=O)CC1
1-(3,5-dimethylisoxazol-4-yl)carbamoylcyclopropanesulfonamide tert-butylcarbamate
收率 100.0%

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他This compound was obtained in a crude 100% yield
  2. 2
    其他The compound was taken directly into the next reaction without purification

实验过程

This compound was obtained in a crude 100% yield according to the procedure described for the synthesis of 1-methoxymethylcyclopropylsulfonylamine tert-butylcarbamate except that 1.20 equivalents of 3,5-dimethylisoxazole-4-isocyanate was used as the electrophile. The compound was taken directly into the next reaction without purification.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: US07935670B2uspto-grants-2011_05