反应 #632008

反应方程式

ethyl acetate

N-tert-butyl-(1-methyl)cyclopropylsulfonamide

benzyl bromide

→

desired product

收率 60.0%

N-tert-butyl-(1-benzyl)cyclopropyl-sulfonamide

收率 60.0%

溶剂

hexane

反应条件

后处理

1. 1
   其他This compound was obtained in 60% yield

实验过程

This compound was obtained in 60% yield using the procedure described for the synthesis of N-tert-butyl-(1-methyl)cyclopropylsulfonamide using 1.05 equivalents of benzyl bromide. Trituration with 10% ethyl acetate in hexane provided the desired product: 1H NMR (CDCl3) δ 0.92 (m, 2H), 1.36 (m, 2H), 1.43 (s, 9H), 3.25 (s, 2H), 4.62 (br s, 1H), 7.29-7.36 (m, 5H).

来源