反应 #631971

反应方程式

2-Carboxyethyl acrylate

Thionyl chloride

→

desired product

3-chloro-3-oxopropyl acrylate

溶剂

CH2Cl2

反应条件

后处理

1. 1
   温度the solution is cooled in an ice bath
2. 2
   其他The solvent is removed under reduced pressure

实验过程

2-Carboxyethyl acrylate (1 eq.) is dissolved in CH2Cl2 and the solution is cooled in an ice bath. Thionyl chloride (1 eq.) is added dropwise and the mixture is allowed to warm to room temperature and stir for 4 hours. The solvent is removed under reduced pressure and the desired product is isolated by vacuum distillation.

来源