反应 #62404

反应方程式

acetic anhydride

4-bromo-5-fluoro-2-methylphenylamine

→

title compound

N-(4-Bromo-5-fluoro-2-methylphenyl)acetamide

反应条件

后处理

1. 1
   workup.DISTILLATIONExcess acetic anhydride was distilled off under reduced pressure
2. 2
   洗涤the precipitated crystals were washed with water

实验过程

73.6 mL of acetic anhydride was added with 80.0 g of 4-bromo-5-fluoro-2-methylphenylamine at room temperature, and stirred at this temperature for 10 minutes. Excess acetic anhydride was distilled off under reduced pressure, and the precipitated crystals were washed with water, to afford 77.6 g of the title compound as colorless crystal.

来源