反应 #619130

ord-dff2831289d04b03b942fa567dcd321b

反应方程式

CCOC(=O)CSc1cnc(NC(=O)N(C2CCCCCC2)C2CCCCC2)s1
[2-(3-Cycloheptyl-3-cyclohexyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid ethyl ester
C1CCCC(NC2CCCCC2)CC1
cyclohexyl-cycloheptylamine
CCOC(=O)CS.Nc1cncs1
5-aminothiazole 2-mercaptoacetic acid ethyl ester
O=C(O)CSc1cnc(NC(=O)N(C2CCCCCC2)C2CCCCC2)s1
title compound
O=C(O)CSc1cnc(NC(=O)N(C2CCCCCC2)C2CCCCC2)s1
[2-(3-Cycloheptyl-3-cyclohexyl-ureido)-thiazol-5-ylsulfanyl]acetic acid

反应条件

详细条件
See reaction.notes.procedure_details.

后处理

  1. 1
    其他Hydrolysis

实验过程

[2-(3-Cycloheptyl-3-cyclohexyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid ethyl ester prepared as described in general procedure (A) using cyclohexyl-cycloheptylamine and 5-aminothiazole-2-mercaptoacetic acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound.

来源

DOI: 10.6084/m9.figshare.5104873.v1专利: USRE045183E1uspto-grants-2014_10