反应 #61835

反应方程式

1-(naphth-1-yl)-1-propanone

phenyltrimethylammonium tribromide

→

2-bromo-1-(naphth-1-yl)-1-propanone

收率 175.6%

溶剂

tetrahydrofuran

反应条件

后处理

1. 1
   其他then partitioned between petroleum ether and aqueous sodium carbonate solution
2. 2
   其他The organic layer was separated
3. 3
   洗涤washed with water, brine
4. 4
   干燥dried with sodium sulphate
5. 5
   过滤filtered
6. 6
   其他evaporated in vacuo

实验过程

To a solution of 1-(naphth-1-yl)-1-propanone (4.0 g) in anhydrous tetrahydrofuran (50 ml) was added phenyltrimethylammonium tribromide (8.0 g). The resulting mixture was stirred overnight at room temperature then partitioned between petroleum ether and aqueous sodium carbonate solution. The organic layer was separated, washed with water, brine, dried with sodium sulphate, filtered and evaporated in vacuo to yield crude 2-bromo-1-(naphth-1-yl)-1-propanone (5.7 g).

来源