反应 #6072

反应方程式

maleic anhydride

phenyl vinyl sulfide

ethylaluminum dichloride

→

title compound

收率 90.7%

2,4-dioxo-6-phenylthio-3-oxabicyclo[3.2.0]heptane

收率 90.7%

溶剂

1,2-dichloroethane

methylene chloride

反应条件

后处理

1. 1
   洗涤The methylene chloride solution was washed three times with saturated aqueous ammonium chloride solution
2. 2
   干燥once with brine, dried over anhydrous sodium sulfate
3. 3
   浓缩concentrated

实验过程

To a solution of maleic anhydride (0.39 g, 4 mmol) and phenyl vinyl sulfide (0.52, 4 mmol) in 17 mL of 1,2-dichloroethane under nitrogen, was added 2 mL (0.5 equiv) of ethylaluminum dichloride. The resultant solution was stirred at ambient temperature for 0.5 h and then diluted with 75 mL of methylene chloride. The methylene chloride solution was washed three times with saturated aqueous ammonium chloride solution and once with brine, dried over anhydrous sodium sulfate and concentrated to give 0.85 g of the title compound; EI-MS, m/e (rel intensity): 234 (M+, 23), 136 (100), 109 (12), 91 (21).

来源