反应 #5974

反应方程式

methyl 2-methoxy-4-amino-5-chlorobenzoate

acetic acid

→

methyl 2-methoxy-4-acetylamino-5-chlorobenzoate

溶剂

acetic anhydride

反应条件

后处理

1. 1
   过滤The reaction mixture is filtered
2. 2
   workup.ADDITIONdiluted with water
3. 3
   过滤filtered
4. 4
   其他evaporated to dryness

实验过程

A mixture of 21 g of methyl 2-methoxy-4-amino-5-chlorobenzoate is stirred in 12 ml acetic anhydride and 100 ml acetic acid at 100° C. for 24 hours. The reaction mixture is filtered, diluted with water, filtered and evaporated to dryness to obtain methyl 2-methoxy-4-acetylamino-5-chlorobenzoate which is used directly in the next step.

来源