反应 #59699

反应方程式

Ammonium chloride

t-Butyloxycarbonylhydrazine

4-bromobenzoyl chloride

DIPEA

DCM

→

4-bromo-benzoic acid N′-(2,2-dimethyl-propionyl)-hydrazide

反应条件

后处理

1. 1
   其他the organic phase was separated
2. 2
   其他dried
3. 3
   其他the solvent evaporated under vacuum

实验过程

t-Butyloxycarbonylhydrazine (1.26 g) was added portionwise to a solution of 4-bromobenzoyl chloride (2.0 g), and DIPEA (2.37 ml) in DCM (20 ml) and the reaction stirred at room temperature for 18 hours. Ammonium chloride solution was added, the organic phase was separated, dried and the solvent evaporated under vacuum to give 4-bromo-benzoic acid N′-(2,2-dimethyl-propionyl)-hydrazide.

来源