反应 #5914

反应方程式

4-Fluoroaniline

potassium carbonate

18-Crown-6

ethylbromoacetate

→

Ethyl N-(4-fluorophenyl)glycine

溶剂

ethanol

ethanol

反应条件

后处理

1. 1
   温度the reaction was heated to reflux

实验过程

4-Fluoroaniline (5 g), potassium carbonate (3.11 g) and a catalytic amount of 18-Crown-6 were stirred together in 50 ml of ethanol. A solution of ethylbromoacetate (7.52 g) in 25 ml of ethanol was added dropwise and the reaction was heated to reflux.

来源