反应 #58425

反应方程式

(2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone

ethyl4-amino-1-piperidine carboxylate

→

title compound

4-[6-Amino-5-(5-fluoro-2-methoxy-4-chloro-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid ethyl ester

反应条件

实验过程

The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone (Example 47) and ethyl4-amino-1-piperidine carboxylate (Aldrich 96%) using the procedure described in Step B. Example 6. HRMS, observed: 451.1545, Calcd for (M+H)+: 451.1543.

来源