反应 #58107

反应方程式

5-benzyloxy-8-(2,2-dihydroxy-acetyl)-4H-benzo[1,4]oxazin-3-one

1-(3-methyl-benzyl)-cyclopropylamine

trifluoroacetate

→

5-hydroxy-8-{1-hydroxy-2-[1-(3-methyl-benzyl)-cyclopropylamino]-ethyl}-4H-benzo[1,4]oxazin-3-one

反应条件

后处理

1. 1
   其他Prepared

实验过程

Prepared according to general method 3 from 329 mg (1 mmol) 5-benzyloxy-8-(2,2-dihydroxy-acetyl)-4H-benzo[1,4]oxazin-3-one and 161 mg (1 mmol) 1-(3-methyl-benzyl)-cyclopropylamine. Yield: 179 mg (37%, trifluoroacetate); mass spectroscopy: [M+H]+=369.

来源